ea0099oc6.4 | Oral Communications 6: Environmental Endocrinology | ECE2024
Provvisiero Donatella
, Negri Mariarosaria
, Amatrudo Feliciana
, Patalano Roberta
, Monto Tatiana
, Pugliese Gabriella
, de Alteriis Giulia
, Graziadio Chiara
, Colao Annamaria
, Pivonello Rosario
, Savastano Silvia
, Pivonello Claudia
Endocrine-disrupting chemicals, including bisphenol A (BPA) may promote obesity. The role of 1,25-Dihydroxyvitamin D3 (VitD) in counteracting adipogenesis is still a matter of question. Thus, the current study aims to investigate whether and how VitD exposure during adipogenesis could prevent the BPA pro-adipogenic effect in adipocyte models: the mouse pre-adipocytes 3T3-L1 and the human adipose-derived mesenchymal stem cells (hAMSC). 3T3-L1 and hAMSC were treated with VitD (1...